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1

Digitalisation of a company decision-making system: a concept for data-driven and fact-based product portfolio management

Hannila, Hannu, Kuula, Seppo, Harkonen, Janne, Haapasalo, Harri

Journal:

Journal of Decision System

Year:

2020

File:

PDF, 1.12 MB

2020

2

Intra-operative application of chlorhexidine gel reduces bacterial counts in internal implant cavity

Ghannad, Farzan, Alkadi, Lubna T., Wiebe, Colin B., Shen, Ya, Haapasalo, Markus, Larjava, Hannu S.

Journal:

European Journal of Oral Sciences

Year:

2015

Language:

english

File:

PDF, 372 KB

english, 2015

3

Magnetization Transfer Imaging of Lumbar Disc Degeneration

Paajanen, Hannu, Komu, Markku, Lehto, llkka, Laato, Matti, Haapasalo, Hannu

Journal:

Year:

1994

File:

PDF, 418 KB

1994

4

Epidermal growth factor receptor signaling suppresses αvβ6 integrin and promotes periodontal inflammation and bone loss

Bi, Jiarui, Koivisto, Leeni, Dai, Jiayin, Zhuang, Deshu, Jiang, Guoqiao, Larjava, Milla, Shen, Ya, Bi, Liangjia, Liu, Fang, Haapasalo, Markus, Häkkinen, Lari, Larjava, Hannu

Journal:

Journal of Cell Science

Year:

2019

Language:

english

File:

PDF, 1.78 MB

english, 2019

5

Cyclin D1 expression in astrocytomas is associated with cell proliferation activity and patient prognosis

Sallinen, Satu-Leena, Sallinen, Pauli K., Kononen, Juha T., Syrj�koski, Kirsi M., Nupponen, Nina N., Rantala, Immo S., Hel�n, Pauli T., Helin, Heikki J., Haapasalo, Hannu K.

Journal:

The Journal of Pathology

Year:

1999

Language:

english

File:

PDF, 266 KB

english, 1999

6

Chromosome imbalances in familial gliomas detected by comparative genomic hybridization

Niina Paunu, Satu-Leena Sallinen, Ritva Karhu, Helena Miettinen, Pauli Sallinen, Juha Kononen, Pekka Laippala, Kalle O.J. Simola, Pauli Helén, Hannu Haapasalo

Journal:

Genes, Chromosomes and Cancer

Year:

2000

Language:

english

File:

PDF, 333 KB

english, 2000

7

Apolipoprotein E–dependent accumulation of Alzheimer disease–related lesions begins in middle age

Eloise Kok, Satu Haikonen, Teemu Luoto, Heini Huhtala, Sirkka Goebeler, Hannu Haapasalo, Pekka J. Karhunen

Journal:

Annals of Neurology

Year:

2009

Language:

english

File:

PDF, 189 KB

english, 2009

8

Low expression of p27 indicates a poor prognosis in patients with high-grade astrocytomas

Ruut M. Kirla, Hannu K. Haapasalo, Hannu Kalimo, Eeva K. Salminen

Journal:

Year:

2003

Language:

english

File:

PDF, 82 KB

english, 2003

9

Cancer incidence in families with multiple glioma patients

Niina Paunu, Eero Pukkala, Pekka Laippala, Risto Sankila, Jorma Isola, Helena Miettinen, Kalle O.J. Simola, Pauli Helén, Heikki Helin, Hannu Haapasalo

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 76 KB

english, 2002

10

Absence of KLF6 gene mutations in human astrocytic tumors and cell lines

Pasi A. Koivisto, Xiaohui Zhang, Satu-Leena Sallinen, Pauli Sallinen, Heikki J. Helin, Jin-Tang Dong, Erwin G. Van Meir, Hannu Haapasalo, Eija-Riitta Hyytinen

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 49 KB

english, 2004

11

KIT overexpression induces proliferation in astrocytes in an imatinib-responsive manner and associates with proliferation index in gliomas

Tea Blom, Heli Fox, Alexandre Angers-Loustau, Karita Peltonen, Laura Kerosuo, Kirmo Wartiovaara, Marika Linja, Olli A. Jänne, Panu Kovanen, Hannu Haapasalo, Nina N. Nupponen

Journal:

International Journal of Cancer

Year:

2008

Language:

english

File:

PDF, 317 KB

english, 2008

12

CRP gene variation affects early development of Alzheimer's disease-related plaques

Eloise Helena Kok, Mervi Alanne-Kinnunen, Karita Isotalo, Teemu Luoto, Satu Haikonen, Sirkka Goebeler, Markus Perola, Mikko A Hurme, Hannu Haapasalo, Pekka J Karhunen

Journal:

Journal of Neuroinflammation

Year:

2011

Language:

english

File:

PDF, 265 KB

english, 2011

13

The value of mitotic counting in the assessment of prognosis and proliferation in human tumours

Yrjö Collan, Hannu Haapasalo, Cecily M. Quinn, Nicholas A. Wright

Journal:

The Journal of Pathology

Year:

1991

Language:

english

File:

PDF, 325 KB

english, 1991

14

Comparison of three quantitation methods for PCNA immunostaining: Applicability and relation to survival in 83 astrocytic neoplasms

Dr. Hannu K. Haapasalo, Pauli K. Sallinen, Pauli T. Helen, Immo S. Rantala, Heikki J. Helin, Jorma J. Isola

Journal:

The Journal of Pathology

Year:

1993

Language:

english

File:

PDF, 641 KB

english, 1993

15

Prognostication of astrocytoma patient survival by Ki-67 (MIB-1), PCNA, and S-phase fraction using archival paraffin-embedded samples

Pauli K. Sallinen, Dr. Hannu K. Haapasalo, Tapio Visakorpi, Pauli T. Helén, Immo S. Rantala, Jorma J. Isola, Heikki J. Helin

Journal:

The Journal of Pathology

Year:

1994

Language:

english

File:

PDF, 638 KB

english, 1994

16

Perinuclear leucine-rich repeats and immunoglobulin-like domain proteins (LRIG1-3) as prognostic indicators in astrocytic tumors

Dongsheng Guo, Jonas Nilsson, Hannu Haapasalo, Olayinka Raheem, Tommy Bergenheim, Håkan Hedman, Roger Henriksson

Journal:

Acta Neuropathologica

Year:

2006

Language:

english

File:

PDF, 471 KB

english, 2006

17

Molecular genetic analysis of theREST/NRSFgene in nervous system tumors

Tea Blom, Olli Tynninen, Marjut Puputti, Maija Halonen, Anders Paetau, Hannu Haapasalo, Minna Tanner, Nina N. Nupponen

Journal:

Acta Neuropathologica

Year:

2006

Language:

english

File:

PDF, 422 KB

english, 2006

18

Differences in aberrant expression and splicing of sarcomeric proteins in the myotonic dystrophies DM1 and DM2

Anna Vihola, Linda L. Bachinski, Mario Sirito, Shodimu-Emmanuel Olufemi, Shohrae Hajibashi, Keith A. Baggerly, Olayinka Raheem, Hannu Haapasalo, Tiina Suominen, Jeanette Holmlund-Hampf, Anders Paetau,

Journal:

Acta Neuropathologica

Year:

2010

Language:

english

File:

PDF, 536 KB

english, 2010

19

Novel myosin heavy chain immunohistochemical double staining developed for the routine diagnostic separation of I, IIA and IIX fibers

Olayinka Raheem, Sanna Huovinen, Tiina Suominen, Hannu Haapasalo, Bjarne Udd

Journal:

Acta Neuropathologica

Year:

2010

Language:

english

File:

PDF, 565 KB

english, 2010

20

CHEK2 mutations in primary glioblastomas

Satu-Leena Sallinen, TarjaI konen, Hannu Haapasalo, Johanna Schleutker

Journal:

Journal of Neuro-Oncology

Year:

2005

Language:

english

File:

PDF, 172 KB

english, 2005

21

Antioxidant enzymes in oligodendroglial brain tumors: association with proliferation, apoptotic activity and survival

Järvelä Sally, Bragge Helena, Paunu Niina, Järvelä Timo, Paljärvi Leo, Kalimo Hannu, Helén Pauli, Kinnula Vuokko, Soini Ylermi, Haapasalo Hannu

Journal:

Journal of Neuro-Oncology

Year:

2006

Language:

english

File:

PDF, 736 KB

english, 2006

22

Antioxidant enzymes in oligodendroglial brain tumors: association with proliferation, apoptotic activity and survival

Sally Järvelä, Helena Bragge, Niina Paunu, Timo Järvelä, Leo Paljärvi, Hannu Kalimo, Pauli Helén, Vuokko Kinnula, Ylermi Soini, Hannu Haapasalo

Journal:

Journal of Neuro-Oncology

Year:

2006

File:

PDF, 114 KB

2006

23

Female predominance in meningiomas can not be explained by differences in progesterone, estrogen, or androgen receptor expression

Katariina Korhonen, Tiina Salminen, Jani Raitanen, Anssi Auvinen, Jorma Isola, Hannu Haapasalo

Journal:

Journal of Neuro-Oncology

Year:

2006

Language:

english

File:

PDF, 224 KB

english, 2006

24

XRCC1andXRCC3variants and risk of glioma and meningioma

Anne Kiuru, Carita Lindholm, Sirpa Heinävaara, Taina Ilus, Päivi Jokinen, Hannu Haapasalo, Tiina Salminen, Helle Collatz Christensen, Maria Feychting, Christoffer Johansen, Stefan Lönn, Beatrice Malme

Journal:

Journal of Neuro-Oncology

Year:

2008

Language:

english

File:

PDF, 213 KB

english, 2008

25

Decreased expression of antioxidant enzymes is associated with aggressive features in ependymomas

Sally Järvelä, Kristiina Nordfors, Miia Jansson, Joonas Haapasalo, Pauli Helén, Leo Paljärvi, Hannu Kalimo, Vuokko Kinnula, Ylermi Soini, Hannu Haapasalo

Journal:

Journal of Neuro-Oncology

Year:

2008

Language:

english

File:

PDF, 306 KB

english, 2008

26

Amplification and overexpression of KIT, PDGFRA, and VEGFR2 in medulloblastomas and primitive neuroectodermal tumors

Tea Blom, Annariikka Roselli, Valtteri Häyry, Olli Tynninen, Kirmo Wartiovaara, Miikka Korja, Kristiina Nordfors, Hannu Haapasalo, Nina N. Nupponen

Journal:

Journal of Neuro-Oncology

Year:

2010

Language:

english

File:

PDF, 256 KB

english, 2010

27

Detection of human herpesvirus-6 in adult central nervous system tumors: predominance of early and late viral antigens in glial tumors

John R. Crawford, Maria Rita Santi, Robbie Cornelison, Satu-Leena Sallinen, Hannu Haapasalo, Tobey J. MacDonald

Journal:

Journal of Neuro-Oncology

Year:

2009

Language:

english

File:

PDF, 788 KB

english, 2009

28

Brain phenotype of carbonic anhydrase IX-deficient mice

Pei-wen Pan, Anna-Kaisa Parkkila, Salla Autio, Mika Hilvo, Raija Sormunen, Silvia Pastorekova, Jaromir Pastorek, Hannu Haapasalo, Seppo Parkkila

Journal:

Transgenic Research

Year:

2012

Language:

english

File:

PDF, 583 KB

english, 2012

29

Cytoplasmic LRIG2 expression is associated with poor oligodendroglioma patient survival

Camilla Holmlund, Hannu Haapasalo, Wei Yi, Olayinka Raheem, Thomas Brännström, Helena Bragge, Roger Henriksson, Håkan Hedman

Journal:

Year:

2009

Language:

english

File:

PDF, 249 KB

english, 2009

30

Expression of Antioxidant Enzymes in Astrocytic Brain Tumors

Hannu Haapasalo, Maarit Kyläniemi, Niina Paunu, Vuokko L. Kinnula, Ylermi Soini

Journal:

Brain Pathology

Year:

2003

Language:

english

File:

PDF, 357 KB

english, 2003

31

Chromogenic in situ hybridization-detected hotspot MYCN amplification associates with Ki-67 expression and inversely with nestin expression in neuroblastomas

Korja, Miikka, Finne, Jukka, Salmi, Toivo T, Kalimo, Hannu, Karikoski, Riitta, Tanner, Minna, Isola, Jorma, Haapasalo, Hannu

Journal:

Modern Pathology

Year:

2005

Language:

english

File:

PDF, 266 KB

english, 2005

32

CDKN2/p16 Predicts Survival in Oligodendrogliomas: Comparison with Astrocytomas

Helena Miettinen, Juha Kononen, Pauli Sallinen, Hannu Alho, Pauli Helen, Heikki Helin, Hannu Kalimo, Leo Paljärvi, Jorma Isola, Hannu Haapasalo

Journal:

Journal of Neuro-Oncology

Year:

1999

Language:

english

File:

PDF, 81 KB

english, 1999

33

Prognostic Value of the Expression of Tumor Suppressor Genes p53, p21, p16 and pRb, and Ki-67 Labelling in High Grade Astrocytomas Treated with Radiotherapy

Ruut Kirla, Eeva Salminen, Sakke Huhtala, Joanne Nuutinen, Lauri Talve, Hannu Haapasalo, Hannu Kalimo

Journal:

Journal of Neuro-Oncology

Year:

2000

Language:

english

File:

PDF, 97 KB

english, 2000

34

Cell Cycle Regulators (p21, p53, pRb) in Oligodendrocytic Tumors: a Study by Novel Tumor Microarray Technique

Helena E. Miettinen, Niina Paunu, Immo Rantala, Hannu Kalimo, Leo Paljärvi, Heikki Helin, Hannu Haapasalo

Journal:

Journal of Neuro-Oncology

Year:

2001

Language:

english

File:

PDF, 778 KB

english, 2001

35

Analysis ofp53 Tumor Suppressor Gene in Families with Multiple Glioma Patients

Niina Paunu, Kirsi Syrjäkoski, Risto Sankila, Kalle O. J. Simola, Pauli Helén, Mika Niemelä, Mika Matikainen, Jorma Isola, Hannu Haapasalo

Journal:

Journal of Neuro-Oncology

Year:

2001

Language:

english

File:

PDF, 99 KB

english, 2001

36

Neurological outcome of childhood brain tumor survivors

Sari Pietilä, Raija Korpela, Hanna L. Lenko, Hannu Haapasalo, Riitta Alalantela, Pirkko Nieminen, Anna-Maija Koivisto, Anne Mäkipernaa

Journal:

Journal of Neuro-Oncology

Year:

2012

Language:

english

File:

PDF, 212 KB

english, 2012

37

Immunohistochemical analysis of LRIG proteins in meningiomas: correlation between estrogen receptor status and LRIG expression

Soma Ghasimi, Hannu Haapasalo, Mine Eray, Katariina Korhonen, Thomas Brännström, Håkan Hedman, Ulrika Andersson

Journal:

Journal of Neuro-Oncology

Year:

2012

Language:

english

File:

PDF, 477 KB

english, 2012

38

Arm-specific multicolor fluorescence in situ hybridization reveals widespread chromosomal instability in glioma cell lines

Satu-Leena Sallinen, Pauli Sallinen, Minna Ahlstedt-Soini, Hannu Haapasalo, Heikki Helin, Jorma Isola, Ritva Karhu

Journal:

Cancer Genetics and Cytogenetics

Year:

2003

Language:

english

File:

PDF, 409 KB

english, 2003

39

Expression of iron-related genes in human brain and brain tumors

Milla M Hänninen, Joonas Haapasalo, Hannu Haapasalo, Robert E Fleming, Robert S Britton, Bruce R Bacon, Seppo Parkkila

Journal:

BMC Neuroscience

Year:

2009

Language:

english

File:

PDF, 1.20 MB

english, 2009

40

Specific expression profile and prognostic significance of peroxiredoxins in grade II-IV astrocytic brain tumors

Sally Järvelä, Immo Rantala, Alejandra Rodriguez, Heini Kallio, Seppo Parkkila, Vuokko L Kinnula, Ylermi Soini, Hannu Haapasalo

Journal:

Year:

2010

Language:

english

File:

PDF, 563 KB

english, 2010

41

The tumour-associated carbonic anhydrases CA II, CA IX and CA XII in a group of medulloblastomas and supratentorial primitive neuroectodermal tumours: an association of CA IX with poor prognosis

Kristiina Nordfors, Joonas Haapasalo, Miikka Korja, Anssi Niemelä, Jukka Laine, Anna-Kaisa Parkkila, Silvia Pastorekova, Jaromir Pastorek, Abdul Waheed, William S Sly, Seppo Parkkila, Hannu Haapasalo

Journal:

Year:

2010

Language:

english

File:

PDF, 1.50 MB

english, 2010

42

Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication

Maija Wolf, Miikka Korja, Ritva Karhu, Henrik Edgren, Sami Kilpinen, Kalle Ojala, Spyro Mousses, Anne Kallioniemi, Hannu Haapasalo

Journal:

Year:

2010

Language:

english

File:

PDF, 1.31 MB

english, 2010

43

Carbonic anhydrase IX in oligodendroglial brain tumors

Sally Järvelä, Seppo Parkkila, Helena Bragge, Marketta Kähkönen, Anna-Kaisa Parkkila, Ylermi Soini, Silvia Pastorekova, Jaromir Pastorek, Hannu Haapasalo

Journal:

Year:

2008

Language:

english

File:

PDF, 654 KB

english, 2008

44

Characterization ofTEM1/endosialinin human and murine brain tumors

Eleanor B Carson-Walter, Bethany N Winans, Melissa C Whiteman, Yang Liu, Sally Jarvela, Hannu Haapasalo, Betty M Tyler, David L Huso, Mahlon D Johnson, Kevin A Walter

Journal:

Year:

2009

Language:

english

File:

PDF, 721 KB

english, 2009

45

Absence of polysialylated NCAM is an unfavorable prognostic phenotype for advanced stage neuroblastoma

Miikka Korja, Anne Jokilammi, Toivo T Salmi, Hannu Kalimo, Tarja-Terttu Pelliniemi, Jorma Isola, Immo Rantala, Hannu Haapasalo, Jukka Finne

Journal:

Year:

2009

Language:

english

File:

PDF, 1.07 MB

english, 2009

46

Fatal dengue virus infection in a Finnish traveler

Eili Huhtamo, Sakari Vuorinen, Nathalie Y. Uzcátegui, Olli Vapalahti, Hannu Haapasalo, Jukka Lumio

Journal:

Journal of Clinical Virology

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

47

Distinct distal myopathy phenotype caused by VCP gene mutation in a Finnish family

Johanna Palmio, Satu Sandell, Tiina Suominen, Sini Penttilä, Olayinka Raheem, Peter Hackman, Sanna Huovinen, Hannu Haapasalo, Bjarne Udd

Journal:

Neuromuscular Disorders

Year:

2011

Language:

english

File:

PDF, 435 KB

english, 2011

48

Desmoplastic infantile ganglioglioma: novel aspects in clinical presentation and genetics

Kimmo Lönnrot, Markku Terho, Veikko Kähärä, Hannu Haapasalo, Pauli Helén

Journal:

Surgical Neurology

Year:

2007

Language:

english

File:

PDF, 249 KB

english, 2007

49

Mutant (CCTG)n Expansion Causes Abnormal Expression of Zinc Finger Protein 9 (ZNF9) in Myotonic Dystrophy Type 2

Olayinka Raheem, Shodimu-Emmanuel Olufemi, Linda L. Bachinski, Anna Vihola, Mario Sirito, Jeanette Holmlund-Hampf, Hannu Haapasalo, Yi-Ping Li, Bjarne Udd, Ralf Krahe

Journal:

The American Journal of Pathology

Year:

2010

Language:

english

File:

PDF, 832 KB

english, 2010

50

Mitosis counting in tumors

Hannu Haapasalo, Yrjö Collan

Journal:

Human Pathology

Year:

1991

Language:

english

File:

PDF, 291 KB

english, 1991

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